Fungal biotransformation of 6-nitrochrysene.

نویسندگان

  • J V Pothuluri
  • J B Sutherland
  • J P Freeman
  • C E Cerniglia
چکیده

The fungus Cunninghamella elegans was used to biotransform 6-nitrochrysene, a mutagen that is a widespread environmental contaminant. After 6 days, 74% of the 3H-labeled 6-nitrochrysene added had been metabolized to two isomeric sulfate conjugates. These conjugates were separated by high-performance liquid chromatography and identified by UV-visible, 1H nuclear magnetic resonance, and mass spectral techniques as 6-nitrochrysene 1-sulfate and 6-nitrochrysene 2-sulfate.

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 64 8  شماره 

صفحات  -

تاریخ انتشار 1998